to search for clinical trials on
the LILACS database using the internet
Numbers | Step-by-step | Webform | Search strategy | References | Contact
|LILACS is the most complete and
frequently updated (CD-ROM every four months: January,
May and September; Internet every month) collection of
databases for recording and disseminating the scientific
production of Latin American and Caribbean Health
professionals. It is the result of a cooperative effort
between the constituent countries.
LILACS is an electronic database (CD-ROM and On-line) that indexes regional literature from more than 670 journals, with 270,244 (40th edition, May 2001) citations incorporated since 1982 with abstracts in are of English, Portuguese or Spanish. Of the 670 journals indexed in LILACS, only 41 overlap with MEDLINE/EMBASE. The United States National Library of Medicine's medical subject headings (MeSH) vocabulary is used to index each LILACS citation. LILACS is edited by BIREME (Latin American and Caribbean Health Science Information Center, http://www.bireme.br), in the city of São Paulo, Brazil. Currently, BIREME is an agency of the Pan-American Health Organization / World Health Organization.
Using the Brazilian Cochrane Centre website (http://www.epm.br/cochrane) you can have free access to the information on how to search the Lilacs database on-line: numbers of records, step-by-step instructions, webform, search strategy for RCTs, references and contact.
In the Cochrane Library 2000, Issue 2, of the 50 Cochrane Review Groups, only four are using the LILACS database (Depression, Anxiety & Neurosis; Hepato-biliary; Infectious Diseases; and Schizophrenia Groups). Just four others: Ear, Nose and Throat disorders; Metabolic and Endocrine Disorders; Neuromuscular Disease and Peripheral Vascular Disease Review Groups mention LILACS as an electronic Database that will be searched in the near future.
With each new edition of LILACS, the Brazilian Cochrane Centre will be locating new RCTs and CCTs for re-tagging Lilacs database and will send these for inclusion on the Cochrane Controlled Trials Register and CENTRAL.
LILACS at a glance!
|Abstract available||114,173 (61%)||143,044 (61%)||148,573 (61%)||153,976 (61%)||161,021 (61%)||166,894 (61%)|
|First step - Construction of the
note differences between formats on the first stage of
|Second step - Copy search strategy
Use Mac or Pc Microsoft
Internet Explorer 4.01 or later
Advanced search webform
Database: LILACS (Latin
American and Caribbean Health Science Literature)
Advanced form adapted
Search Strategy for Clinical Trials
(Bireme interface of the internet)
The strategy is divided into three stages:
stage one (red words) includes terms with high
precision, stage two (green words) includes terms
with moderate precision, and stage three (blue words) includes terms
with low precision but which provide optimal sensitivity.
((Pt randomized controlled trial OR Pt controlled clinical trial OR Mh randomized controlled trials OR Mh random allocation OR Mh double-blind method OR Mh single-blind method) AND NOT (Ct animal AND NOT (Ct human and Ct animal)) OR (Pt clinical trial OR Ex E05.318.760.535$ OR (Tw clin$ AND (Tw trial$ OR Tw ensa$ OR Tw estud$ OR Tw experim$ OR Tw investiga$)) OR ((Tw singl$ OR Tw simple$ OR Tw doubl$ OR Tw doble$ OR Tw duplo$ OR Tw trebl$ OR Tw trip$) AND (Tw blind$ OR Tw cego$ OR Tw ciego$ OR Tw mask$ OR Tw mascar$)) OR Mh placebos OR Tw placebo$ OR (Tw random$ OR Tw randon$ OR Tw casual$ OR Tw acaso$ OR Tw azar OR Tw aleator$) OR Mh research design) AND NOT (Ct animal AND NOT (Ct human and Ct animal)) OR (Ct comparative study OR Ex E05.337$ OR Mh follow-up studies OR Mh prospective studies OR Tw control$ OR Tw prospectiv$ OR Tw volunt$ OR Tw volunteer$) AND NOT (Ct animal AND NOT (Ct human and Ct animal)))
AA, Clark OAC, Atallah AN. Optimal search
strategy for clinical trials in the Latin American and
Caribbean Health Science Literature Database (LILACS
database): Update [Letter]. Sao Paulo Med
J/Rev Paul Med 1999;117(3):138-9.
2) Castro AA, Clark OAC, Atallah AN. Optimal Search Strategy for Clinical Trials in the Latin American and Caribbean Health Science Literature Database (LILACS). Sao Paulo Med J/ Rev Paul Med 1997;115(5):1423-6. Medline Record
3) Dickersin K, Scherer R, Lefebvre C. Identifying relevant studies for systematic reviews. BMJ 1994;309:1286-9. Medline Record
4) Clarke M, Oxman AD, editors. Optimal search strategy for RCTs. Cochrane Reviewers Handbook 4.0 [updated July 1999]; Appendix 5c. Section 4. In: Review Manager (RevMan) [Computer program]. Version 4.0. Oxford, England: The Cochrane Collaboration, 1999. From Dickersin K, Larson K. Establishing and maintaining an international register of RCTs. In: The Cochrane Library. Oxford: Update Software, 1996.
5) Castro AA, Atallah AN, Clark OA. .Locating and Appraising Systematic Reviews [letter, comment]. Ann Intern Med 1998;128(4):322-3. Comment on: Ann Intern Med 1998;126(7):532-8.
6) Lowe HJ, Barnett GO. Understanding and using the Medical Subject Heandings (MeSH) vocabulary to perform literature searches. JAMA 1994;271(14):1103-1108.
7) Soares K, Adams C. Searching non-Anglophone databases II: developing a search strategy for LILACS (abstract). Proceedings of the IV Cochrane Coloquium; 1996 Oct 15-19; Adelaide, Australian.
suggestions and criticisms will be welcome!
Send to: Aldemar Araujo Castro
Brazilian Cochrane Centre
Universidade Federal de São Paulo/Escola Paulista de Medicina
Rua Pedro de Toledo 598
04039-001 São Paulo, SP. Brazil.
Phone: (+55 11) 5575 2970
Fax: (+55 11) 5579 0469
editor: Aldemar Araujo Castro
Last update: 20 June 2001 Next update: 20 December 2001